2D Enantioselective Disposable Stochastic Sensor for Fast Real-Time Enantioanalysis of Glutamine in Biological Samples
نویسندگان
چکیده
As protein is both a structural component and metabolic intermediary, amino acids play crucial function in the body. When it comes to proteins, only L-configuration of chiral found. At molecular level, symmetry disrupted; however, scientific basis for this breaking not yet known. Enantioanalysis compounds such as plays very important role correct diagnosis illnesses, cancer. The enantiomers glutamine—a acid—were investigated biological samples using disposable stochastic sensor. sensor based on immobilization maltodextrin (DE 4.0–7.0) surface graphene decorated with Ag was designed, characterized, validated screening tests whole blood tissue samples. designed cold plasma deposition plastic material. enantioselective, being able discriminate between glutamine. High sensitivities were recorded enantiomers, while limits determination 100 fmol L−1 L-glutamine 1 D-glutamine. recoveries determined assay one enantiomer presence other, despite ratio two enantiomers.
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ژورنال
عنوان ژورنال: Symmetry
سال: 2023
ISSN: ['0865-4824', '2226-1877']
DOI: https://doi.org/10.3390/sym15050958